产品货号:
Z17281
中文名称:
Gelsolin/GSN抗体
英文名称:
Anti-Gelsolin/GSN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Gelsolin/GSN Antibody |
指标别名 | Actin depolymerizing factor;ADF;AGEL;Brevin;Gelsolin;GSN |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat,monkey |
应用范围 | WB,IHC,ICC/IF,FCM |
基因名称 | GSN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Gelsolin recombinant protein (Position:E580-A782).Human Gelsolin shares 94% and 95% amino acid (aa) sequences identity with mouse and rat Gelsolin,respectively. |
实际分子量 | 86KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Gelsolin,also known as GNS or brevin,is an actin-binding protein that is a key regulator of actin filament assembly and disassembly.Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily.The gene was assigned to human chromosome 9q33.2.It is the principal intracellular and extracellular actin-severing protein.Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis.Gelsolin may have therapeutic potential as a mucolytic agent in CF patients.The antiapoptotic activity of gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol. |
Uniprot ID | P06396 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | gelsolin |
蛋白名全称 | Gelsolin |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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