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产品目录

Gelsolin/GSN抗体图片
产品货号:
Z17281
中文名称:
Gelsolin/GSN抗体
英文名称:
Anti-Gelsolin/GSN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Gelsolin/GSN Antibody
指标别名Actin depolymerizing factor;ADF;AGEL;Brevin;Gelsolin;GSN
克隆性Polyclonal
检验物种human,mouse,rat,monkey
应用范围WB,IHC,ICC/IF,FCM
基因名称GSN
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Gelsolin recombinant protein (Position:E580-A782).Human Gelsolin shares 94% and 95% amino acid (aa) sequences identity with mouse and rat Gelsolin,respectively.
实际分子量86KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Gelsolin,also known as GNS or brevin,is an actin-binding protein that is a key regulator of actin filament assembly and disassembly.Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily.The gene was assigned to human chromosome 9q33.2.It is the principal intracellular and extracellular actin-severing protein.Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis.Gelsolin may have therapeutic potential as a mucolytic agent in CF patients.The antiapoptotic activity of gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol.
Uniprot IDP06396
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称gelsolin
蛋白名全称Gelsolin
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:Gelsolin/GSN抗体Gelsolin抗体GSN多抗Anti-Gelsolin/GSN Antibody
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